COMBINED ANALYSIS OF RRBS DNA METHYLOME AND TRANSCRIPTOME REVEAL NOVEL CANDIDATE GENES RELATED TO PORCINE CLOSTRIDIUM PERFRINGENS TYPE C-INDUCED DIARRHEA

Combined Analysis of RRBS DNA Methylome and Transcriptome Reveal Novel Candidate Genes Related to Porcine Clostridium perfringens Type C-Induced Diarrhea

Clostridium perfringens type C (Cp) is one of the principal microorganisms responsible for bacterial diarrhea in neonatal and pre-weaning piglets.To better understand the molecular effects of Cp infection, we performed a genome-wide comparison of the changes in DNA methylation and gene expression in Cp infected resistant and susceptible piglets.We

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Discrete Dynamic Model of the Mammalian Sperm Acrosome Reaction: The Influence of Acrosomal pH and Physiological Heterogeneity

The acrosome reaction TBH TONE SOFTENER (AR) is an exocytotic process essential for mammalian fertilization.It involves diverse physiological changes (biochemical, biophysical, and morphological) that culminate in the release of the acrosomal content to the extracellular medium as well as a reorganization of the plasma membrane (PM) that allows spe

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